BOP2: Bayesian Optimal Phase II Design with Simple and Complex Endpoints

Version: V1.0.0 ; Last Updated: 06/20/2017


Heng Zhou, Ying Yuan and Jack J. Lee

Department of Biostatistics,MD Anderson Cancer Center


Endpoints:

Interims:

Null Hypothesis:

Null Hypothesis:

Null Hypothesis:

Null Hypothesis:

Null Hypothesis:

Alternative Hypothesis:

Alternative Hypothesis:

Alternative Hypothesis:

Alternative Hypothesis:

Alternative Hypothesis:

Type I error rate:


Simulation scenarios:

Scenario 2

Scenario 3

Scenario 4

Scenario 5

Scenario 6

Scenario 7

Scenario 8

Scenario 9

Scenario 10

The maximum number of scenarios you can enter is 10

Simulation scenarios:

Scenario 2

Scenario 3

Scenario 4

Scenario 5

Scenario 6

Scenario 7

Scenario 8

Scenario 9

Scenario 10

The maximum number of scenarios you can enter is 10

Simulation scenarios:

Scenario 2

Scenario 3

Scenario 4

Scenario 5

Scenario 6

Scenario 7

Scenario 8

Scenario 9

Scenario 10

The maximum number of scenarios you can enter is 10

Simulation scenarios:

Scenario 2

Scenario 3

Scenario 4

Scenario 5

Scenario 6

Scenario 7

Scenario 8

Scenario 9

Scenario 10

The maximum number of scenarios you can enter is 10

Simulation scenarios:

Scenario 2

Scenario 3

Scenario 4

Scenario 5

Scenario 6

Scenario 7

Scenario 8

Scenario 9

Scenario 10

The maximum number of scenarios you can enter is 10


Note: Calculate the stopping boundaries and run the simulation using the same endpoint before downloading the protocol template; otherwise, the download button is disabled.

Download protocol template
Download protocol template
Download protocol template
Download protocol template
Download protocol template