PID:880; v2.1.1 ; Last Updated: 08/31/2017

Bayesian Toxicity Monitoring

This application is developed by: J. Jack Lee, Ying-Wei Kuo, Diane Liu and Nan Chen

Department of Biostatistics

Calculate Stopping Boundaries

Toxicity parameters:
Probability of Dose-limiting Toxicity (\(\theta\))
Prior distribution for \(\theta\): \(\textit{Beta}\)(\(a_0, b_0\))
Sample and cohort size:
Toxicity stopping criterion:
Stop for excessive toxicity
\(\textit{Prob}\)(\(\theta\ > \theta_{max}\)) \(\ge P_T\)





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Operating Characteristics

Scenarios:
(separate by a comma)
Graph Parameters:
(separate by a comma)





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Trial Monitoring

Seq#
Patient ID
Toxicity Outcome
1
2


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